acujoint

acujoint-package-1

Acujoint

 

Joints have joint kinesthetic receptors around the lining of the joint that respond to the pressure. Joint kinesthetic receptors detect when we are putting too much strain on a joint and they stimulate the pain nerve fibres that communicate with the brain. When we injure ourselves or suffer inflammatory conditions like joint pain, the immune system makes a variety of chemicals that transmit pain signals to the brain. These chemicals include the prostaglandins, cytokines, interleukotrienes and peptides.  These chemicals lead to acute inflammatory conditions. Nature has given many potential herbs and spices that can cure the inflammatory disease conditions. Our novel formulation incorporates the idea of traditional Ayurveda with most modern technology. The novel ingredients and their mechanism of action are mentioned below:

Benefits of Acujoint:

  • Highly Efficient formulation with natural  bio actives
  • Made with patent pending PNS technology, Patents pending in US and India
  • Supports the structural integrity and motility of joint cartilage
  • Rejuvenates joint cartilage by inhibiting 5-lipoxygenase activity
  • Supports flexibility of joints
  • Compared the efficiency with Glucosamine chondroitin standard
  • Clinically proven in healthy human volunteers
  • Suggested serving size of just 500mg/day
  • Lesser serving size and economic compared to available formulations

Product design:

Made by patent pending PNS (Polar Nonpolar sandwich) Technology

The design of Acujoint is aimed developing a natural phytochemical formulation for maintaining healthy joints.

Suggested serving size: 500mg/day

Turmeric

 

turmeric

The anti inflammatory action of the curcumin can be mainly attributed due to the following reasons. Curcumin has the potential to inhibit the leukotrienes which are the possible mediators of many inflammatory disorders. Curcumin also inhibited the NF-ƙB activity that contribute to many inflammatory disorders. Reactive oxygen and reactive nitrogen species which play a crucial role in the damage of joint cartilages are inhibited by curcumin. Tumor necrosis factor (TNF-α) has a crucial role in many inflammatory conditions.   Curcumin has the potential to inhibit the TNF activity there by promoting a healthy joint.

Beta caryophyllene:

 

pepper

The sesquiterpene (E)-β-Caryophyllene [(E)-BCP]  is a major plant volatile found in large amounts in the essential oils of many different spice and food plants, such as oregano (Origanum vulgare L.) and black pepper (Piper nigrum L.). Beta Caryophyllene is a dietary cannabinoid. The beta Caryophyllene binds to the CP55, 940 binding site (i.e., THC binding site) of the peripheral hCB2 cannabinoid receptor and thereby preventing the possible factor for inflammation.

3-o- acetyl 11-keto beta boswellic acid(AKBA)

bosewella

Boswellia AKBA supports the structural integrity, motility and comfort of joint cartilage and promotes gastrointestinal health and cell health. Boswellic acids maintain healthy 5-lipoxygenase (5-LO) activity, moderating leukotriene biosynthesis. Study suggests that of the various boswellic acids, 3-acetyl-11-keto-beta-boswellic acid, or AKBA, is considered as the most powerful. It may also play a role in maintaining healthy matrix Metalloproteinase (MMP) activity, supporting connective tissue structural composition

Alpinia galangal Extract:

 

galangal

From ancient days onwards, the extract of Alpinia galangal is found to be used in anti inflammatory formulations. Study of phytochemical constituents have shown that the rhizome contains 1’ S’-1’ acetoxychavicol acetate, 1’ S-1’-hydroxychavicol acetate, trans-p-hydroxycinnamaldehyde. The active principle 1’S’-1’ acetoxychavicol acetate has been reported to possess various activities like anti-inflammatory, antioxidative, antimicrobial, and antioxidative activities.